Activity

Meeting with TriCore Laboratories Tricore & UTAK Vitamin D Cals October 03, 2025 • 22 mins • View Meeting or Ask Fathom ACTION ITEMS ✨ Send Levy-Jennings data w/ current values for UTAK stock vit D controls to Andrew Meyer, Christina Create quote options (trial order + 1yr vol) for custom vit D cals. Design: ~10/80/150 ng/mL, 1mL/wk usage. Send to all 3 TriCore contacts early-mid next wk Andrew Hartmann MEETING SUMMARY ✨ General Template Customize • Change Template Meeting Purpose Discuss potential custom vitamin D calibrator material from UTAK for TriCore Laboratories. Key Takeaways • TriCore is interested in UTAK's custom vitamin D calibrators due to sourcing issues with their current supplier • UTAK can potentially meet TriCore's 10% specification requirement, pending review of current QC data • TriCore to provide UTAK with current QC data for comparison; UTAK to prepare quote options • Further discussion needed on calibrator design, pricing, and quality considerations before final decision Topics Current Vitamin D Calibrator Situation • TriCore facing difficulties sourcing vitamin D calibrator material from Chrome Systems • Chrome Systems lost U.S. distributor; orders now go directly to Germany • International shipping and tariffs causing additional challenges • TriCore temporarily stopped in-house vitamin D testing due to supply issues UTAK Custom Calibrator Capabilities • Can manufacture batch to TriCore's specifications • Typical acceptance criteria is ±25% from target, but most stock materials within 10% • Proposed guarantee of ±10% from verified value instead of target value • Ability to include both D2 and D3 analytes consistently Calibrator Design and Specifications • Proposed design: 3-point cal with levels at approximately 10, 80, and 150 ng/mL • Similar to TriCore's current 3-point cal from Chrome Systems • TriCore's assay range: 5-180 ng/mL • Controls needed around medical decision levels (20-30 ng/mL and above 100 ng/mL) Product Stability and Storage • Frozen option: 18 months frozen stability, 25-day in-use stability, stored at -10°C • Freeze-dried option: 30 months lyophilized stability, 25-day in-use stability, refrigerated storage Matrix Options • 100% real human serum (requires baseline testing) • SMX serum matrix (hormone and vitamin-free, starts at zero value) • Option for completely negative serum available Quality Considerations • TriCore prefers changing QC and calibrator lots at different times to avoid perpetuating bias • Concerns about using same supplier for both calibrators and controls • UTAK uses third-party labs (e.g., NMS, MedTox) for independent testing Next Steps • Christina to send UTAK current QC data for comparison with UTAK's verified values • UTAK to prepare quote options based on ~1 mL/week usage, including minimum trial order and 1-year volume • UTAK to send quote to all TriCore participants (Christina, Melissa, Larry) by early-mid next week • Schedule follow-up meeting to review quote and address questions • Consider long-term potential for custom QC materials in addition to calibrators View Meeting → Ask Fathom! Ask our AI Assistant for answers and insights. It's ChatGPT for your meetings! Try Ask Fathom → © Fathom 2025. All Rights Reserved. Unsubscribe